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Core Technology
CHIRAL TECHNOLOGIES scientists are continually pushing the frontiers of chiral knowledge and consistently publishing their discoveries. Here is a representative sampling of the technical publications of our staff:

Lynam KG, Stringham RW. Chiral separations on polysaccharide stationary phases using polar organic mobile phases. Chirality. 2005 (in press).

Preparative Enantioselective Chromatography, edited by Geoffrey B. Cox, Blackwell Publishing, Ltd., Oxford, UK, © 2005.

tringham RW. Chiral separations of amines in subcritical fluid chromatography using polysaccharide stationary phases and acidic additives. J Chromatogr. 2005;1070:163-170.

Stringham RW. The use of polysaccharide phases in the separation of enantiomers. Adv Chromatog. 2005;44 (in press).

Stringham RW, Lynam KG, Lord BS. Memory effect of diethylamine mobile phase additive on chiral separations on polysaccharide stationary phases. Chirality. 2004;16:493-498.

Stringham RW, Ye YK. Chiral separations of amines in high performance liquid chromatography using polysaccharide stationary phases and acidic additives. J Chromatogr. 2005 (submitted).

Tachibana K, Ohnishi A. Reversed-phase liquid chromatographic separation of enantiomers on polysaccharide type chiral stationary phases. J Chromatogr A. 2001;906(1-2):127-54.

Ye YK, Lynam KG, Stringham RW. The effect of amine mobile phase additives on chiral supercritical fluid chromatography using polysaccharide stationary phases. J Chromatogr. 2004;1041:211-217.

Ye YK, Stringham RW, Wirth M. Origin of enhanced chiral selectivity by acidic additives for a polysaccharide-based stationary phase. J Chromatogr. 2004;1057:75-82.

Immobilized Column References

Zhang T, Franco P. Analytical and preparative potential of immobilized polysaccharide-derived chiral stationary phases, edited by G. Subramanian. Chiral Separation Techniques – A Practical Approach, third ed., Wiley-VCH, Weinheim, Germany. 2006;3:99-134.

Zhang T, Kientzy C, Franco P, Ohnishi A, Kagamihara Y, Kurosawa H. Solvent versatility of immobilized 3,5-dimethylphenylcarbamate of amylose in enantiomeric separations by HPLC. J. Chromatogr A. 2005;1075:65-75.

Zhang T, Nguyen D, Franco P. Use of Evaporative Light Scattering Detector in the detection and quantification of enantiomeric mixtures by HPLC. J Sep Sci. 2006;29:1517-1524.

Zhang T, Nguyen D, Franco P, Isobe Y, Michishita T, Murakami T. Cellulose tris(3,5-dichlorophenylcarbamate) immobilised on silica: A novel chiral stationary phase for resolution of enantiomers. J Pharm Biochem Anal. in press (doi:10.1016/jpba.2007.06.008).

Zhang T, Nguyen D, Franco P, Murakami T, Ohnishi A, Kurosawa H. Cellulose 3,5-dimethylphenylcarbamate immobilized on silica: A new chiral stationary phase for the analysis of enantiomers. Anal Chim Acta. 2006;557:221-228.

Zhang T, Schaeffer M, Franco P, Optimization of the chiral separation of a Ca-sensitizing drug on an immobilized polysaccharide-based chiral stationary phase – Case study with a preparative perspective.
J. Chromatogr A. 2005;1083:96-101.

 
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